Hyperosmolar Nonketotic State in a patient with Type 1 Diabetes Mellitus A Bhattacharyya, A Howell, A Lakhdar Dreschfeld described the major comas in diabetes mellitus in an address to the Manchestor Medical Society in 1881 as three different syndromes: Diabetic Collapse, The alcoholic form of diabetic coma and Coma from acetonemia. He described diabetic collapse […]

Treatment of Thyroid Diseases A Bhattacharyya and HM Buckler. The treatment of thyroid diseases is relatively straightforward. True thyroid problems should be distinguished from sick euthyroid syndrome and due consideration, should be given to the patient’s age, gender, family and wishes in making treatment decisions. Treatment of thyroid diseases falls in to three main categories. […]

DIGAMI in a district general hospital in the UK Bhattacharyya A, Vice PA The mortality and morbidity in diabetic in diabetic patients with AMI is higher than in non – diabetic population (2). The proven benefit of a number of interventions (Aspirin, betablocker, thrombolysis, ACE inhibitor, etc) for the acute event implies a major advantage […]

The Aetiology and Pathology of Thyroid Disease A Bhattacharyya and PG Wiles The Thyroid gland is one of the largest endocrine organs, weighing approximately 15-20g in adults. The gland is composed of closely packed sacs, called acini or follicles, which are invested with a rich capillary network. The interior of the follicle is filled with […]

Screening for genetic haemochromatosis in blood samples with raised alanine aminotranferase M Bhavani, D Lioyd, A Bhattacharyya, J Marples, P Elton, M Worwood In the UK approximately 1 in 140 people are homozygous for the C282Y mutuation of the HFE gene and are at risk from iron overload caused by genetic haemochromatosis (GH). Early detection […]

Ruptured Ectopic Pregnancy presenting with hyperglycaemia A Bhattacharyya, DJ Tymms. The incidence of ectopic pregnancy has been rising the world over. In the UK, the incidence has doubled in the decade 1980-1990; at present about 8000 ectopic pregnancies are treated each year. The diagnosis of ectopic pregnancy remains a challenge to the clinician. Quite often […]

Evolving electrocardiographic changes in patient with hyperthyroidism A Bhattacharyya, K Kaushal and TL Dorman A 28 year old man, motor mechanic by profession, was admitted via the casualty department with a two day history of central chest pain radiating to both shoulders. He had no medical history of note; he smoked 50 cigarettes per day […]