Mitochondrial defects and Endocrine dysfunction

by A Bhatatcharyya, DJ Tymms Quaternary Journal of Medicine 1998:91:375-6. Hypoparathyroidism is referred as a recently-described endocrinopathy associated with mitochondrial disorders. We have seen a patient with proven MELAS syndrome who has NIDDM, bilateral optic atrophy, and sensorineural deafness, stroke like episode, myoclonic seizure, short stature, intestinal pseudo-obstruction, lactic acidaemia, and primary hypoparathyroidism.


What is Hypocalcaemia? Low level of Calcium in the blood is called Hypocalcaemia. Normal blood Calcium is 8.5 – 10.2 mg/dl. In normal health blood calcium is maintained in this range and the normal mechanism is that most of the Calcium is bound to albumin (proteins) and hence before assessing the normal calcium levels , […]