Dr Arpan Bhattacharyya

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Home » Pituitary » Everything you wanted to know about Hypogonadism

Everything you wanted to know about Hypogonadism

April 24, 2020 by admin

Normally two Pituitary hormones known as LH and FSH are responsible for stimulating Testes and Ovaries in men and women respectively. Any cause of hypopituitarism can cause hypogonadism.

Hypogonadism can decrease other hormones secreted by the gonads including progesterone, DHEA, anti-Müllerian hormone, activin, and inhibin. Sperm development (spermatogenesis) and release of the egg from the ovaries (ovulation) may be impaired by hypogonadism, which, depending on the degree of severity, may result in partial or complete difficulty or inability to have children.

In MenIn Women
Loss of body, facial and pubic hairDecrease in size of breast
Increased breast tissue (gynaecomastia) Lack of pubic and axillary hairs
Reduced testicular sizeAbsent or irregular period
Smooth, fine wrinkly skin, especially on the faceHot Flushes
Erectile dysfunction , InfertilityLow or absent sex drive

What are the investigations required?

  • Blood Tests
    • LH, FSH, Prolactin
    • Testosterone/ Oestradiol
  • Imaging – MR scan of Pituitary gland

What are the treatment options?

For men  –   Androgen replacement orally or by injection.

For women,

  • Cyclical estrogen progesterone preparations
  • Gonadotrophin preparations

Related

Filed Under: Pituitary Tagged With: Erectile dysfunction, Hypogonadism, libido, Oestrogen, Testosterone

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