Diabetes Aetiology

Aetiology and Pathology of Type 2 Diabetes Mellitus

A Bhattacharyya

Diabetes Mellitus (DM) is a group of metabolic disorders characterized by raised blood sugar due to defects in insulin secretion, action or both. The chronic hyperglycaemia of DM is associated with longterm damage, dysfunction and failure of organs, such as the eyes, kidneys, nerves, blood vessels and heart. The first organized attempt to develop diagnostic criteria was probably carried out by the National Diabetes Data Group in 1979. Later in 1985, the diagnostic criteria were modified by the World Health Organisation (WHO). These criteria were followed until the recent modification recommended by an expert committee.

Hospital Pharmacist 2001;85-9.