Control of Adrenal Gland

Control of Secretion: Cortisol is secreted in response to a stimulating hormone called adrenocorticotropic hormone (ACTH) from the master gland ‘pituitary’ situated in the brain. ACTH is itself secreted under control of the hypothalamic peptide corticotropin-releasing hormone (CRH). Aldosterone is controlled by the body’s sodium, potassium and water concentrations.

Diseases resulting from abnormalities of this pituitary and adrenal axis either cause a deficiency status or excess status of the hormone cortisol.